Seems to me the answer is obvious.
In order to simplify the question, lets assume a new global business is in place. I trust you can see where I'm leading to.
New global businesses, have several required capabilities that almost enforce you to by in the cloud. Capabilities like scalability from infrastructure point of view and economic point of view (pay as you grow), integration, multi-X (language, currency etc) and many more.
Grown up startups in the cloud providing SaaS solutions for businesses "push" them gently into the cloud, making more and more businesses completely virtual.
Some of the good cloud services that can easily replace existing private infrastructure:
LaunchRock - Soft launch for new business
MailChimp - Mail automation
Amazon EC2 - Infrastructure for servers
GitHub - Source configuration management for software source code sharing
Atlassian Suite - Knowledge sharing, Issue management and CRM.
SalesForce.com - CRM and Sales management
Google Apps - Mail, Docs and many others for office management
DropBox / Google Drive - File sharing (did anyone say Disk On Key? What is it?)
join.me - Meeting online and desktop sharing.
There are so many other good cloud services - Please share and comment.
Ronen
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